- Area: 5 335 km2
- Population: 823 173
- Population density: 154
- Regional Capital: Ústí nad Labem
- Number of districts: 7 (Děčín, Chomutov, Litoměřice, Louny, Most, Teplice, Ústí nad Labem)
- Number of villages: 354
- Borders with: Germany, Liberec Region, Central Bohemia Region, Plzeň Region, Karlovy Vary Region
- Highest point: 1 113 m.n.m. (Macecha)
- Lowest point: 115 above sea level (the Labe river in Hřensko)